Extramammary Paget’s Disease (CK7)

Mohs Surgery | Mohs Specialist | Houston | The Woodlands | Springs | Katy

(EMPD) Extramammary Paget’s disease is a uncommon neoplastic condition of apocrine gland-bearing skin and its occurrence in combination with Bowen’s disease is very rare. The most common site of involvement is the vulva, although perineal, perianal, scrotal and penile skin may also be affected. EMPD is usually not combined with Bowen’s disease. We report an interesting case of EMPD combined with Bowen’s disease, which was confirmed by immunohistochemical stain.

(EMPD) Extramammary Paget’s disease is rare and affects individuals between the ages of 50 and 80 years old. The most frequently affected site is the vulva, followed by perineal, perianal, scrotal and penile skin regions. Vulval EMPD represents 1% to 5% of all vulval malignancies, with a peak age incidence of 65 years3,4. The most common histologic type of squamous cell carcinoma in situ in the vulval area is Bowen’s disease. If the lesion does not respond to topical therapy within 6 weeks, biopsy should be performed to exclude EMPD. But, concomittent expression of both diseases at the same lesion is very rare.

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Texas Surgical Dermatology PA
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Spring, TX 77379

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